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腐植酸是一类大分子芳香有机弱酸,其钠盐可溶于水。许多国家以泥炭浴方式用于治疗关节炎、皮肤炎症和妇产科炎症。近年来我国亦试用于临床,局部外用,对于皮炎湿疹类皮肤病、外眼炎症、外科感染创面、宫颈糜烂、阴道炎等以炎症为主要特征的一些疾病有效。国内外的研究工作已证明,泥炭腐植酸属于非甾体类抗炎药。本文从抗炎角度研究山东薛城风化煤腐植酸的药理活性,为其在临床上作为抗炎药物应用提供药理学实验根据。
Humic acid is a type of macromolecular aromatic organic weak acid whose sodium salt is soluble in water. Many countries use peat baths to treat arthritis, skin inflammation and gynecological inflammation. In recent years, China has also been used clinically and locally for external use. It is effective for some diseases characterized by inflammation, such as dermatitis and eczema skin diseases, external ocular inflammation, surgical infections, cervical erosion, and vaginitis. Research work at home and abroad has proven that peat humic acid is a non-steroidal anti-inflammatory drug. This article studies the pharmacological activity of humic acid from weathering coal in Xuecheng, Shandong Province, and provides pharmacological experimental basis for its application as an anti-inflammatory drug in clinical practice.