两栖类和鸟类的听器支持细胞能够重新进入细胞周期增殖分化或直接转分化为新生毛细胞,并有不同程度功能的恢复,哺乳类内耳的前庭毛细胞也见到这种现象。在这个过程中,某些激发因素在刺激支持细胞发生表型转化中,发挥了重要的功能。本文就这些激发因素的作用做一综述,为哺乳类内耳的耳蜗毛细胞的再生研究提供参考。 Amphibians and birds’ hearing cell support cells can re-enter the cell cycle to proliferate and differentiate, or directly transdifferentiate into newborn hair cells, with different degrees of functional recovery. The phenomenon is also observed in the vestibular hair cells of mammalian inner ear. In this process, some of the motivational factors play an important role in stimulating the phenotypic transformation of supporting cells. This article reviews the role of these stimuli and provides a reference for the regeneration of cochlear hair cells in mammalian inner ear.