六年前Kahn 等报道了在严重抗胰岛素型的特殊的糖尿病患者(称B 型)的血清中,存在有胰岛素受体的抗体。这种抗体可以抑制胰岛素与其受体的结合,并且有类似胰岛素的生物活性,如促进葡萄糖的氧化、抑制脂肪的分解等。这一发现,对于糖尿病的临 Six years ago Kahn et al. Reported the presence of insulin receptor antibodies in sera of patients with severe, insulin-resistant diabetes (type B). This antibody can inhibit the insulin binding to its receptor, and insulin-like biological activity, such as the promotion of glucose oxidation, inhibition of fat decomposition and so on. This finding is for the immediate onset of diabetes