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[目的]探讨控制性降压、急性高容量血液稀释(AHH)及回收式自体输血在颅内肿瘤外科手术中的应用价值.[方法]回顾性分析 2016 年 1 月至 2018 年 1 月本院收治的 82 例颅内肿瘤患者的临床资料,根据输血方法的不同将其分为观察组(控制性降压+ AHH +回收式自体输血,n=43)和对照组(控制性降压+ AHH,n=39).观察两组 AHH 前即刻(T0 )、AHH 后 30 min(T1 )、AHH 后 60 min(T2 )和手术结束时(T3 )患者的心率(HR)、平均动脉压(MAP)、中心静脉压(CVP)等指标.[结果]两组手术时间、术中出血量比较差异无统计学意义(P>0.05);观察组未输异体血比例明显高于对照组,差异有统计学意义(P0.05);the proportion of non-transfused blood in the observation group was significantly higher than that in the control group (P<0.05).The MAP at T1 and T2 in the observation group and the control group was significantly higher than that at T0 ,and the CVP at T1 and T2 in the observation group was significantly higher than that in the control group (P <0.05).Postoperative fibrinogen (FIB) was lower in the two groups than that before operation,while prothrombin time (PT)and activated partial thrombin time (APTT)were significantly higher than those before operation (all P0.05).[Conclusion]Controlled hypotension combined with AHH and recycled autologous blood transfusion have better appli-cation value in intracranial tumors surgery.It can reduce the situation of allogeneic blood transfusion and has little effect on hemodynamics and coagulation function.