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目的:分析研究复方小茴香蜜膏治疗肾孟肾炎的临床疗效。方法:回顾性分析2010年1月至2012年1月在我院治疗的52例肾盂肾炎患者的临床资料。将52例患者随机分为治疗组和对照组各26例,治疗组患者给予复方小茴香蜜膏治疗,对照组给予左氧氟沙星治疗,观察记录两组患者用药后的临床疗效和不良反应。结果:治疗组痊愈10例,显效13例,总有效率为88.46%;对照组痊愈8例,显效32例,总有效率为69.23%,两组比较差异有统计学意义(x2=3.214,P<0.05);治疗组对大肠埃希菌、粪肠球菌、阴沟肠杆菌及铜绿假单胞菌的控制率远高于对照组(P<0.05);治疗组2例出现皮疹,1例出现腹泻,对照组2例出现皮疹,两组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论:复方小茴香蜜膏治疗肾盂肾炎安全、高效,值得在临床推广应用。
Objective: To analyze the clinical efficacy of compound fennel cream in the treatment of nephritis. Methods: The clinical data of 52 patients with pyelonephritis treated in our hospital from January 2010 to January 2012 were retrospectively analyzed. Fifty-two patients were randomly divided into treatment group and control group, with 26 cases in each group. The patients in treatment group were given compound fennel cream and the control group were given levofloxacin. The clinical efficacy and adverse reactions were observed and recorded in both groups. Results: The treatment group recovered in 10 cases, markedly effective in 13 cases, the total effective rate was 88.46%; control group recovered in 8 cases, 32 cases markedly effective, the total effective rate was 69.23%, the difference between the two groups was statistically significant (x2 = 3.214, P <0.05). The control rates of Escherichia coli, Enterococcus faecalis, Enterobacter cloacae and Pseudomonas aeruginosa in the treatment group were much higher than those in the control group (P <0.05). In the treatment group, 2 cases had a rash and 1 case had diarrhea In the control group, 2 patients had a rash. There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion: The compound fennel honey cream is safe and effective in the treatment of pyelonephritis, which is worthy of clinical application.