阻塞性睡眠呼吸暂停低通气综合征患者腭舌比值与症状程度的相关性分析

来源 :山东大学耳鼻喉眼学报 | 被引量 : 0次 | 上传用户:backpacker
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目的探讨软腭长度与舌体厚度比值的大小和阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者症状轻重高低的关系,并与传统Friedman分型比较。方法纳入研究的OSAHS患者110名,均采用螺旋CT自前颅底至甲状软骨水平区域进行连续扫描,选取硬腭正中矢状位三维重建图像分析,应用计算机辅助测图工具测量硬腭后缘至悬雍垂尖端长度,以及颏嵴至舌中后1/3交接点(即舌盲孔处)舌体厚度,并计算软腭长度与舌体厚度比值。分析该比值与多导睡眠呼吸监测(PSG)检查结果的关系,并与Friedman分型比较。结果 1软腭长度与舌体厚度比值与OSAHS病情严重程度低通气指数(AHI)数值呈显著正相关(r=0.313,P=0.001);与Friedman分型呈负相关(r=-0.196,P=0.041);2在不同AHI分度组间比较,软腭长度与舌体厚度比值有显著差异(F=3.478,P=0.019);3在不同Friedman分型组间比较,软腭长度与舌体厚度比值有显著差异(t=2.131,P=0.035)。4多元逐步回归分析证实软腭长度与舌体厚度比值是AHI大小的显著影响因素(R=0.265,F=19.333,P=0.001)。结论 OSAHS患者AHI与软腭长度与舌体厚度的比值呈明显正相关性,即随软腭长度与舌体厚度的比值增大,OSAHS病情严重程度也增加,同时其与传统Friedman分型有一定的一致性。 Objective To investigate the relationship between the ratio of soft palate length to tongue thickness and the severity of symptoms in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) and to compare with the traditional Friedman classification. Methods A total of 110 OSAHS patients were enrolled in the study. All cases were scanned continuously from the anterior skull base to the level of thyroid cartilage by spiral CT. The mid-sagittal reconstruction of the palatal palate was selected for image analysis. The posterior edge of the hard palate was measured by computer- The length of the tip, and the thickness of the lingual plexus between the chin ridge and the posterior 1/3 point of the tongue (ie, the blind hole of the tongue), and calculates the ratio of the soft palate length to the tongue thickness. The relationship between the ratio and polysomnography (PSG) was analyzed and compared with Friedman classification. Results 1 The ratio of soft palate length to tongue thickness was significantly and positively correlated with the low severity of OSAHS (r = 0.313, P = 0.001), but negatively correlated with Friedman classification (r = -0.196, P = 0.041) .2 There was a significant difference in the ratio of soft palate length to tongue thickness (F = 3.478, P = 0.019) between different AHI index groups. 3 Compared with different Friedman classification groups, the ratio of soft palate length to tongue thickness ratio There was a significant difference (t = 2.131, P = 0.035). 4 Multiple stepwise regression analysis confirmed that the ratio of soft palate length to tongue thickness was a significant factor influencing AHI size (R = 0.265, F = 19.333, P = 0.001). Conclusions There is a positive correlation between AHI and the ratio of soft palate length to tongue thickness in patients with OSAHS. The severity of OSAHS also increases with the ratio of soft palate length to tongue thickness, and it is consistent with the traditional Friedman classification Sex.
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