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目的了解2007年广东省性病实验室梅毒血清学检测能力的总体情况,分析影响检测能力的相关因素和存在问题。方法制备并发放梅毒血清样本,各性病实验室按照分级管理要求,分别做非梅毒螺旋体和梅毒螺旋体血清学定性和定量试验,统计分析各实验室的检测结果。结果2007年,共计186家性病实验室参与了非梅毒螺旋体定性(930份)和定量(930份)样本的检测,其中104家实验室同时进行了梅毒螺旋体定性(520份)和定量(520份)样本的检测,共计2 900份样本中,符合的2 650份,全省总体符合率为91.4%。非梅毒螺旋体和梅毒螺旋体血清学定性试验的总体符合率分别为94.7%和95.4%,两者的假阴性率和假阳性率分别只有6.3%和3.8%、7.4%和0.5%。非梅毒螺旋体和梅毒螺旋体血清学定量试验总体符合率分别为92.7%和91.2%,总体几何标准差分别为2.29和2.57。结论全省性病实验室梅毒血清学总体检测能力较好,但仍需加强室内质控,促进梅毒血清学检测能力的进一步提高。
Objective To understand the overall situation of syphilis serological test in STD laboratory in Guangdong Province in 2007 and to analyze the related factors and existing problems that affect the test ability. Methods The syphilis serum samples were prepared and distributed. According to the requirements of grading management, the laboratories of STDs were respectively used for qualitative and quantitative serological tests of non-Treponema pallidum and Treponema pallidum, and the results of the laboratories were statistically analyzed. Results In 2007, a total of 186 STD laboratories were involved in the qualitative (930) and non-Treponema (930) samples of non-Treponema pallidum, of which 104 laboratories performed both qualitative (520) and quantitative ) Sample test, a total of 2 900 samples, 2 650 copies, the province’s overall compliance rate was 91.4%. The overall coincidence rates of non-Treponema pallidum and Treponema pallidum serological qualitative tests were 94.7% and 95.4%, respectively. The false negative rate and false positive rate were only 6.3%, 3.8%, 7.4% and 0.5% respectively. The overall coincidence rates of non-Treponema pallidum and Treponema pallidum serological quantitative tests were 92.7% and 91.2%, respectively, and the overall geometric standard deviations were 2.29 and 2.57, respectively. Conclusion The STD serology in the STD laboratory is better overall, but it still needs to improve the quality control of the syphilis and further improve the serological detection ability of syphilis.