氯胺酮广泛用于小儿各个领域的麻醉,它具有良好的镇痛效果,特别适合小儿短小手术的麻醉。但氯胺酮麻醉后也存在一些不可忽视的不良反应,除恶心、呕吐等外,其最突出的特点是在麻醉苏醒期内肢体不自主运动较常见[1],具有发生意外伤害的潜在危险。帕瑞昔布钠(parecoxib sodium)是高选择性环氧化酶2(COX-2)抑制药,具有良好镇静作用。 Ketamine is widely used in anesthesia in all fields of children, it has a good analgesic effect, especially suitable for short pediatric anesthesia. However, ketamine also has some non-negligible adverse effects after anesthesia. In addition to nausea and vomiting, the most prominent feature is that involuntary limb movements during anesthesia and awakening are more common [1], with the potential risk of accidental injury. Parecoxib sodium is a highly selective cyclooxygenase 2 (COX-2) inhibitor with good sedation.