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基于枸橼酸咖啡因标准用药方案,结合临床用药经验设计了三种常规用药方案及两种个性用药方案.利用药物动力学模型给定的血药浓度随时间变化规律,以有效治疗浓度为判据,分析了方案的可行性.结合临床用药案例分析了有效用药周期.
Based on the standard dosage regimen of citrate caffeine and the experience of clinical drug use, three conventional regimens and two personalized regimens were designed.Using pharmacokinetic model to determine the change of plasma concentration with time, According to the analysis of the feasibility of the program.Combined with clinical cases of drug use effective period.