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作者用肌肉刺激器通0.75~3.0伏的脉冲直流电,以每秒20次的頻率,刺激志願受試者的舌尖,用面积为2平方厘米、厚1/4厘米吸滿一定体积局部麻醉药的吸收棉盖在舌尖粘膜表面,从受試者感到舌尖麻刺的情况来观察各种药物的作用与效力。在研究中作者設法消除了一些可能干扰結果的因素;如温度、湿度、其他刺激,溶液的体积、味道和温度,接触的时間,预先給药等。局部麻醉作用的时间至少用6名受試者求得,取其均值,結果如下: 1.局部麻醉药的浓度增加时,其作用出現时間加快、持續时間增长;但过度增加浓度,并不能提高局部
The authors used a muscle stimulator through a pulsed DC of 0.75 to 3.0 volts to stimulate the tongue of a volunteer subject at a rate of 20 times per second with a volume of 2 cm 2 and a quarter cm thick to fill a volume of local anesthetic Absorb the cotton cover on the surface of the mucosa of the tongue and observe the effect and potency of various drugs from the feeling of the tongue tingling on the subject. In the study, the authors sought to eliminate some of the factors that could interfere with the outcome; such as temperature, humidity, other stimuli, volume of solution, taste and temperature, time of exposure, pre-dosing and the like. The local anesthetic time was calculated from at least 6 subjects and the mean was taken. The results were as follows: 1. When the concentration of local anesthetic was increased, the effect appeared to be accelerated and the duration increased; however, the concentration was excessively increased and Can not improve the local