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三苯氧胺（ＴＡＭ）在乳腺癌综合治疗中占有重要地位，是目前临床应用最广泛最有效的内分泌治疗药物，也是术后辅助治疗的常用药物。１９７７年美国ＦＤＡ通过批准ＴＡＭ用于临床治疗进展期乳腺癌，几年后用于原发性乳腺癌的辅助治疗［１］。本文综述了ＴＡＭ在乳腺癌治疗中的?
Tamoxifen (TAM) plays an important role in the comprehensive treatment of breast cancer. It is currently the most widely used and most effective endocrine therapy drug, and it is also a commonly used drug for postoperative adjuvant therapy. In 1977, the US FDA approved TAM for the clinical treatment of advanced breast cancer, and several years later for the adjuvant treatment of primary breast cancer [1]. This article reviews the TAM in the treatment of breast cancer?