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目的了解安徽大别山区全民食盐加碘防治碘缺乏病（简称ＩＤＤ）效果和儿童碘营养、甲状腺功能的变化。方法对大别山区霍山县太平畈乡５所小学的８４９名７～１４岁儿童，进行了加碘前及加碘１年后的尿碘、甲状腺肿大率、血清ＦＴ３、ＦＴ４、ＴＧ、ｓＴＳＨ及ＴＲＨ－ＳＴ的对比研究。结果甲肿率明显下降（Ｐ＜０ ００１），以７～８岁儿童最为显著。甲肿率随年龄增长而增加，且同年龄组中女性高于男性（Ｐ＜０．０１）。加碘前、后尿碘＜１００μｇ／Ｌ的分别占５．５％及４．４％，尿碘＞４００μｇ／Ｌ的分别占１６．０％及４０．０９％，加碘后尿碘＜４００μｇ／Ｌ的各组甲肿率均明显下降（Ｐ＜０．００１），而尿碘＞４００μｇ／Ｌ组下降不显著（Ｐ＞０．０５）。加碘前，大别山区Ｔｇ水平稍高于中位数。加碘１年后，尿碘水平明显升高（Ｐ＜０．０１），但Ｔｇ水平明显下降（Ｐ＜０．００５）。加碘前ＦＴ４有７２％高于正常高值，加碘１年后明显下降（Ｐ＜０．００１），且随着尿碘增高，ＦＴ４呈下降趋势（Ｐ＜００５）。与加碘前相比，ＴＢＨ兴奋试验３０ｍｍ的ｓＴＳＨ明显增加（Ｐ＜０．００５）。结论全民碘盐对７～１４岁儿童作用显著，对７～８岁儿童效果更为明显。女生比男生患甲肿的?
Objective To understand the effect of salt iodization on prevention and cure of iodine deficiency disorders (IDD) and iodine nutrition and thyroid function in children in Dabie Mountain, Anhui Province. Methods A total of 849 children aged 7-14 years from 5 primary schools in Taiping Township, Taoshan District of Huoshan County were enrolled in this study. Urinary iodine, goiter, serum FT3, FT4, TG, sTSH, Comparative study of TRH-ST. Results The rate of goiter was significantly decreased (P <0.001), most notably in children aged 7-8 years. The rate of goiter increased with age, and women in the same age group were higher than men (P <0.01). Before and after iodine treatment, urinary iodine <100μg / L accounted for 5.5% and 4.4% respectively, urinary iodine> 400μg / L accounted for 16.0% and 40.09% respectively, urinary iodine <400μg / L group were significantly decreased (P <0.001), while urinary iodine> 400μg / L group did not decline significantly (P> 0.05). Pre-iodine, the Dabie mountain Tg slightly higher than the median. After 1 year of iodine treatment, urinary iodine level increased significantly (P <0.01), but Tg level decreased significantly (P <0.005). FT4 was significantly higher than normal before treatment in 72% of FT4 patients, and decreased significantly after 1 year of iodine treatment (P <0.001). With the increase of urinary iodine, FT4 showed a decreasing trend (P <0.05). Compared with pre-iodine, TBH stimulation test 30mm sTSH increased significantly (P <0.005). Conclusion Whole-body iodized salt has a significant effect on children aged 7 to 14 years and is more effective on children aged 7 to 8 years. Girls suffering from swollen than boys?