论文部分内容阅读
PURPOSE: To report the optical coherence tomography (OCT)-findings in two cases of presumed congenital simple retinal pigment epithelial (RPE) hamartoma. DESIGN: Observational case report. METHODS: Fundus examination, fluorescein angiography, ultrasonography, and OCT were done on two cases of simple RPE hamartoma. RESULTS: A heavily pigmented solitary macular lesion was noted in the right eye of a 22-year old man and a 55-year-old woman. The young man had a foveal lesion and a vision of 10/200; the woman with eccentric lesion had a vision of 20/20. The lesions blocked fluorescence on angiogram; sonography showed hyper-reflective nodules. OCT demonstrated full-thickness retinal replacement, complete optical shadowing, and abrupt margins of the lesion in both the cases, and vitreomacular adhesion at the temporal margin of the foveal lesion. CONCLUSIONS: Congenital simple RPE hamartoma may rarely occur at the foveal center, resulting in poor visual acuity. OCT is a useful non-invasive adjunct for diagnosis of this rare tumor and may reveal additional features like vitreoretinal adhesion.
PURPOSE: To report the optical coherence tomography (OCT) -findings in two cases of presumed congenital simple retinal pigment epithelial (RPE) hamartoma. DESIGN: Observational case report. METHODS: Fundus examination, fluorescein angiography, ultrasonography, and OCT were done on two cases of simple RPE hamartoma. RESULTS: A heavily pigmented solitary macular lesion was noted in the right eye of a 22-year old man and a 55-year-old woman. The young man had a foveal lesion and a vision of 10/200 ; the woman with eccentric lesion had a vision of 20/20. The lesions blocked fluorescence on angiogram; sonography showed hyper-reflective nodules. OCT demonstrated full-thickness retinal replacement, complete optical shadowing, and abrupt margins of the lesion in both the cases , and vitreomacular adhesion at the temporal margin of the foveal lesion. CONCLUSIONS: Congenital simple RPE hamartoma may occur at the foveal center, resulting in poor visual acuity. OCT is a useful non-invasive adj. unct for diagnosis of this rare tumor and may reveal additional features like vitretinal adhesion.