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目的:探讨急性心肌梗死(AMI)患者急诊介入治疗术(PCI)后慢血流发生的影响因素。方法:回顾性分析我院2010年1月至2011年6月于我院诊断为AMI并行急诊PCI治疗的488例患者的临床及冠脉介入治疗影像资料,其中慢血流组(TIMI≤2级)51例,正常血流组(TIMI3级)437例;分析两组临床特点的差别。结果:与正常血流组比较,慢血流组术中血栓抽吸(75.3%比60.8%)、血小板糖蛋白IIb/IIIa受体拮抗剂应用(81.7%比68.6%)比例显著减小,植入支架总长度显著增加[(31.8±12.2)mm比(35.7±12.0)mm],P均<0.05。多因素Log istic回归分析表明,术中血栓抽吸和总支架长度是慢血流发生的独立影响因素(P均<0.05)。结论:PCI术中血栓抽吸和总支架长度是慢血流发生的独立影响因素。
Objective: To investigate the influencing factors of slow blood flow in patients with acute myocardial infarction (AMI) after emergency interventional therapy (PCI). Methods: The clinical and PCI data of 488 patients diagnosed as AMI concurrent emergency PCI in our hospital from January 2010 to June 2011 were analyzed retrospectively. Among them, the group of slow blood flow (TIMI≤2 ) 51 cases, normal blood flow group (TIMI3 grade) 437 cases; analysis of the clinical characteristics of the two groups differences. Results: Compared with the normal blood flow group, the proportion of thrombus aspiration (75.3% vs 60.8%) and platelet glycoprotein IIb / IIIa receptor antagonist (81.7% vs 68.6%) in the slow blood flow group was significantly decreased The total length of stenting increased significantly ([(31.8 ± 12.2) mm vs (35.7 ± 12.0) mm], P <0.05. Multivariate Logistic regression analysis showed that intraoperative thrombus aspiration and total stent length were independent factors of slow blood flow (all P <0.05). Conclusions: Thrombus aspiration and total stent length during PCI are independent predictors of slow blood flow.