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肺发育不良发生率约占总出生儿的1.4％,在死产中占6.7％,在早期新生儿死亡中占15％～20％。其诊断必须根据出生后临床表现和尸解。新生儿尸解包括测量肺重量/体重比,肺内DNA含量,终未小支气管的肺泡数等。临床诊断标准包括重度呼吸障碍,肺部X线检查呈钟型肺或小肺,横膈上升,气胸等。出生前可通过B超检查和胎儿呼吸样运动的有无进行判定。胎儿检查的各项指标各有所长,Yoshimura等报道TC/AC(胸围/腹围)比在灵敏度和特异性上最佳。长谷川等报道有胸水和膈疝的肺发育不良,其LT比(肺与胸廓断面面积比)可用于出生前诊断。另一方面,Blott等报道在长期胎膜早
The prevalence of pulmonary dysplasia accounts for about 1.4% of all births, 6.7% of stillbirths, and 15% to 20% of early neonatal deaths. The diagnosis must be based on clinical manifestations after birth and autopsy. Neonatal autopsy, including the measurement of lung weight / body weight ratio, DNA content in the lungs, the end of the bronchial alveolar number. Clinical diagnostic criteria include severe respiratory disorders, pulmonary X-ray showed bell-type lungs or small lungs, diaphragmatic ascent, pneumothorax and so on. Before birth can be determined by B-ultrasound and fetal breathing-like exercise. Various indicators of fetal examination have their own strengths, Yoshimura et al reported that TC / AC (chest / abdominal circumference) than the sensitivity and specificity of the best. Hasegawa and other reports of pleural effusion and diaphragmatic hernia lung dysplasia, its LT ratio (lung and thoracic cross-sectional area) can be used for prenatal diagnosis. On the other hand, Blott et al. Reported that the long-term fetal membranes were early