近年研究证实胃幽门螺杆菌(Helicobacterpylori,HP)感染和许多常见上胃肠道疾病有关,但HP传染途径尚未明确。尽管流行病学资料支持Hp感染可能通过粪一口传播,但至今经大量试验尚未能从粪便中分离培养出HP,这提示十二指肠液(下称肠液)对HP有杀菌作用。我们进行体外和体内两组实验以探讨肠液对HP的影响。 Recent studies have confirmed that Helicobacter pylori (HP) infection and many common upper gastrointestinal diseases, but HP infection has not yet been identified. Although epidemiological data support that H. pylori infection may be transmitted via fecal infection, up to now, numerous experiments have not been able to isolate and culture HP from the feces, suggesting that duodenal juice (hereinafter referred to as intestinal juice) has a bactericidal effect on HP. We conducted two in vitro and in vivo experiments to investigate the effect of intestinal fluid on HP.