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为探讨影响缺血性脑卒中复发的危险因素，采用以医院为基础的队列研究，对近５年缺血性脑卒中住院病人７７４例进行随访调查，经ＣＯＸ比例风险模型分析，结果显示：糖尿病史（ＲＲ：３．１６，Ｐ＜０．００１）、家族卒中史（ＲＲ：１．５５，Ｐ＜０．０５）、阿司匹林服用情况（ＲＲ：２．３８，Ｐ＜０．００１）及血压控制情况（ＲＲ：１．５９，Ｐ＜０．００１）为影响复发的独立危险因素。提示在缺血性脑卒中二级预防工作中，可将糖尿病史及家族卒中史作为识别高危复发人群的重要标志，病后长期服用阿司匹林及规律服用降压药是预防复发有效的干预措施。
In order to explore the risk factors affecting the relapse of ischemic stroke, we used a hospital-based cohort study to investigate the 774 inpatients with ischemic stroke in the past 5 years. By the COX proportional hazards model, the results showed that: (RR: 3.16, P <0.001), family history of stroke (RR: 1.55, P <0.05), aspirin use (RR: 2.38, Control (RR: 1.59, P <0.001) was an independent risk factor for relapse. These results suggest that diabetes and family history of stroke may be used as an important marker to identify high-risk recurrence in secondary prevention of ischemic stroke. Long-term aspirin treatment and antihypertensive drugs regularly are effective interventions to prevent relapse.