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本文报道了97例疟疾患者丙型肝炎病毒(HCV)感染的原因。发现疟疾患者抗-HCV阳性率为71.13%,其中有单采血浆还输血细胞(下称单采浆)献血史者为89.71%,有受血史者为64.29%,既无单采浆史又无受血史者无一例抗-HCV阳性。有单采浆史的疟疾患者与同村非疟疾的单采浆献血者相比,抗-HCV阳性率无显著不同,且二者均显著高于同村既无单采浆史又无受血史的非疟疾人群。在无单采浆史和受血史人群中,疟疾病例和非病例抗-HCV阳性率很低。说明有单采浆史的疟疾病例HCV感染与单采浆有关,有受血史的疟疾病例HCV感染与受血有关。对当地单采浆血站进行调查,发现在采血、分离血浆和血细胞还输过程中存在血液交叉污染,这是导致有单采浆史的疟疾病例HCV感染的主要原因。
This paper reports the causes of hepatitis C virus (HCV) infection in 97 malaria patients. The positive rate of anti-HCV in patients with malaria was 71.13%. There were 89.71% blood donors with apheresis plasma-transfused cells (hereinafter referred to as apheresis plasma) and 64.29% with blood donors, both There is no case of anti-HCV positive without plasma collection history without blood history. There was no significant difference in anti-HCV positive rates between malaria patients with single plasmapheresis and non-malaria single-plasmapheresis donors in the same village, and both were significantly higher than those with neither plasmapheresis nor blood donation Non-malaria population. Malaria cases and non-case-positive anti-HCV positive rates were very low in those with no history of plasma collection and blood donation. This shows that a single plasmodium-resistant case of malaria was associated with apheresis in HCV infection. Malaria cases with blood-borne history of HCV infection were associated with blood transfusions. A local plasma clotting station was investigated and found to have cross-contamination of blood during blood collection, separation of plasma and blood transfusions, which is the main cause of HCV infection in malaria cases with a history of single plasma.