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目的探讨和分析卡前列素氨丁三醇注射液(安列克注射液)预防剖宫产术中及产后出血的临床有效性和安全性。方法 138例行剖宫产产妇,随机分为甲组和乙组,各69例。甲组产妇给予安列克注射液,乙组产妇给予缩宫素,对比甲乙两组产妇的产时出血量、产后24 h出血量以及出血率。结果甲组产妇产时出血量(219.51±21.31)ml少于乙组产妇(272.61±25.61)ml,差异有统计学意义(t=13.2391,P=0.0000<0.05)。甲组产妇产后24 h内出血量(103.51±20.18)ml少于乙组产妇(137.26±24.81)ml,差异有统计学意义(t=8.7662,P=0.0000<0.05)。甲组产妇出血率(2.90%)低于乙组产妇(13.04%),差异有统计学意义(χ~2=4.8404,P=0.0278<0.05)。结论在剖宫产术中、产后出血的预防中,安列克注射液的应用效果很好,有效降低了产妇产时以及产后的出血量,并且降低了产妇产后出血率,值得推广。
Objective To investigate and analyze the clinical efficacy and safety of carboprost tromethamine injection (Anileike injection) in preventing cesarean section and postpartum hemorrhage. Methods 138 cases of cesarean section were randomly divided into group A and group B, 69 cases each. A group of women given Aileike injection, the second group of women given oxytocin, compared with the second group of two maternal labor-time bleeding, postpartum 24 h bleeding and bleeding rate. Results A group of maternal labor-time bleeding (219.51 ± 21.31) ml less than the B group (272.61 ± 25.61) ml, the difference was statistically significant (t = 13.2391, P = 0.0000 <0.05). The amount of bleeding in group A was less than that in group B (103.51 ± 20.18) ml within 24 h postpartum (137.26 ± 24.81) ml, the difference was statistically significant (t = 8.7662, P = 0.0000 <0.05). Group A maternal hemorrhage rate (2.90%) lower than the B group (13.04%), the difference was statistically significant (χ ~ 2 = 4.8404, P = 0.0278 <0.05). Conclusions In the prevention of postpartum hemorrhage during cesarean section, the application of Aileike Injection is very effective, effectively reducing the amount of bleeding during and after delivery, and reducing the postpartum hemorrhage rate, which is worth promoting.