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[目的]了解皖北农村地区获得性免疫综合征(AIDS)病人抗病毒治疗依从性现状及其相关因素。[方法]整群抽取皖北3县(临泉、界首、萧县)农村地区正在服用抗病毒药物的AIDS病人,通过入户的方式进行询问调查和现场观察。[结果]研究发现,农村地区AIDS病人抗病毒治疗的服药依从性低于90%的有21人,占15.1%,调查时服用人数最多的药物为司他夫定(Stavudine),药物依从性最好的为茚地那韦(indinavir)。服药者中有35人因为忘记而出现间断性停药,占85.4%。多因素Logistic分析显示,服药者身体越差服药依从性越好,而督导医生的水平差、服药者经常出现希望自己死了才好的念头则服药依从性差。[结论]该地区AIDS病人抗病毒治疗服药依从性不高,并受多种因素影响,应大力开展有针对性的健康教育及抗病毒治疗前的服药依从性教育。
[Objective] To understand the current situation and related factors of anti-virus treatment compliance of patients with acquired immune syndrome (AIDS) in rural areas of northern Anhui. [Methods] The AIDS-infected patients who were taking antiviral drugs in rural areas of 3 counties in North Anhui (Linquan, Jieshou and Xiaoxian) were enrolled in this study. The questionnaires were surveyed and observed on site. [Results] The study found that AIDS patients in rural areas with anti-HIV treatment medication adherence of less than 90% of 21 people, accounting for 15.1% of the surveyed patients taking the largest number of drugs Stavudine (Stavudine), drug compliance Good for indinavir. 35 of those taking medication discontinued the drug because of forgetting, accounting for 85.4%. Multivariate logistic analysis showed that the worse the medication compliance was, the worse the medication compliance was, the worse the level of supervising doctors and the frequent occurrence of those who wanted to die were better. [Conclusion] The anti-virus treatment in AIDS patients in the area is not compliant and depends on many factors. Efforts should be made to carry out targeted health education and drug compliance education before anti-virus treatment.