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淋巴细胞增生紊乱是器官和骨髓移植的并发症,如不及时发现和治疗可危及生命。该病为多种组织B淋巴细胞增生所致。作者报道了2例移植后CT上表现为肝弥漫性结节性疾病的病例,肝活检均为淋巴细胞增生紊乱。例1,2岁女性,肝移植后3个月,肝活检为排斥反应,给予大量免疫抑制剂治疗,但肝功能仍异常,重复肝活检示多克隆B淋巴细胞聚集,符合淋巴细胞增生紊乱,细菌和真菌培养均阴性。CT上肝为弥漫分布小于5mm的小结节,US检查阴性,减少免疫抑制剂剂量,再次
Lymphoproliferative disorder is a complication of organ and bone marrow transplantation, which can be life-threatening if not detected and treated in time. The disease is caused by a variety of tissue B lymphocyte proliferation. The authors reported two cases of post-transplant CT manifestations of diffuse diffuse nodular disease in liver biopsy were lymphocytic hyperplasia. Cases of 1,2-year-old women, 3 months after liver transplantation, liver biopsy rejection, given a large number of immunosuppressive agents, but the liver function is still abnormal, repeated liver biopsy showed polyclonal B lymphocyte aggregation, in line with lymphocyte proliferation disorders, Bacteria and fungi were negative. CT on the liver for the diffuse distribution of small nodules smaller than 5mm, US test negative, reduce the dose of immunosuppressive agents, again