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目的分析妊娠期糖尿病(GDM)患者胰岛素分泌水平与超敏C反应蛋白(hs-CRP)之间的关系,以探讨hsCRP与GDM的相关性。方法选择2015年6月至2016年6月在我院妇产科规范产检的GDM患者49例作为研究对象,同期正常健康孕妇50例作为对照组,检测两组hs-CRP水平以及胰岛素分泌水平,分析hs-CRP与GDM的相关性。结果 GDM组的hs-CRP水平明显高于对照组,差异有统计学意义(P﹤0.05);Pearson相关分析显示,GDM组的血浆胰岛素水平与hs-CPR水平呈正相关(r=0.809,P﹤0.000)。结论 GDM组的血浆胰岛素水平与hs-CPR水平呈正相关,检测血清hs-CRP可以作为评估GDM病情严重程度的指标。
Objective To analyze the relationship between insulin secretion and hs-CRP in patients with gestational diabetes mellitus (GDM) to explore the correlation between hsCRP and GDM. Methods From June 2015 to June 2016, 49 cases of GDM patients undergoing obstetrics and gynecology in our hospital were selected as research objects. 50 healthy pregnant women in the same period were taken as control group. The levels of hs-CRP and insulin secretion, Analysis of hs-CRP and GDM correlation. Results The level of hs-CRP in GDM group was significantly higher than that in control group (P <0.05). Pearson correlation analysis showed that there was a positive correlation between plasma insulin level and hs-CPR level in GDM group (r = 0.809, P < 0.000). Conclusions Plasma insulin level in GDM group is positively correlated with hs-CPR level. Serum hs-CRP level can be used as an index to assess the severity of GDM.