恶性颗粒细胞瘤是一种极其罕见的软组织肿瘤，发生于喉者极为罕见。由于其组织形态与良性颗粒细胞瘤非常相似，很难诊断。我们仅遇见１例，报告如下。１　临床资料患者，女，２５岁。１９９６年１０月无明显原因声音嘶哑，在当地医院对症治疗无效。１９９７年１月感呼吸困难， Malignant granulosa cell tumor is an extremely rare soft tissue tumor, occurs in the larynx is extremely rare. Because of its very similar morphology and benign granulosa cell tumor, it is difficult to diagnose. We met only 1 case, the report is as follows. 1 clinical data, female, 25 years old. October 1996 No obvious reason Hoarseness, symptomatic treatment in the local hospital is invalid. In January 1997 a sense of difficulty breathing,