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作者复查所在医院1972～1982年的31例坏死性筋膜炎患者。严格按照有迅速扩散的皮肤感染史,广泛的皮下坏死和水肿,但其下仍有少量肌肉等条件者定为急性皮肤坏疽。对所选择的病例要去除索因条件,故将手术后坏死性筋膜炎、腿部慢性动脉或静脉溃疡有继发感染、以及影响正常防御机理导致身体衰弱的任何伴发疾病病例均除外。这样,剩下6名过去身体健康而只是自发地或在轻微外伤后出现的严重坏死性筋膜炎患者留作分析。 6例患者中4例最近有轻微外伤史。6例患者始发症状均为非特异性炎症或浅表静脉炎,均服用过治疗剂量的非类固醇抗炎药物。2例患者因持续性炎症给过类固醇激素。4例患者接受1种以上非类固醇抗炎药物,其中2例接受包括阿斯匹林在内
The authors reviewed 31 patients with necrotizing fasciitis in their hospital from 1972 to 1982. In strict accordance with the rapid spread of skin infections, extensive subcutaneous necrosis and edema, but there are still a small amount of muscle under the conditions such as acute skin gangrene. Excision of the condition of choice for the selected cases, so necrotizing fasciitis after surgery, leg chronic venous or venous ulcer secondary infection, and affect the normal defensive mechanism leading to weakness of any concomitant disease cases were excluded. In this way, six patients with severe necrotizing fasciitis that had been healthy but only spontaneously or after minor trauma were left for analysis. Of the 6 patients, 4 had a history of minor trauma recently. All 6 patients had nonspecific inflammation or superficial phlebitis and had received a therapeutic dose of non-steroidal anti-inflammatory drugs. Two patients had steroid hormones due to persistent inflammation. Four patients received more than one non-steroidal anti-inflammatory drug, two of which received aspirin