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为了解幽门螺杆菌（ＨｅｌｉｃｏｂａｃｔｅｒＰｙｌｏｒｉ，ＨＰ）感染时机体的免疫状况，我们对１３４例上消化道疾病患者的血清免疫球蛋白进行了检测。结果表明，细菌培养阳性患者的三种血清抗体滴度显著高于细菌培养阴性患者。血清ＩｇＧ、ＩｇＡ、ＩｇＭ阳性与细菌培养阳性的符合率分别为７９．１％，７４．６％和４３．２％。活动性胃炎和非活动性胃炎的细菌培养阳性率分别为６６％和４２％。证实ＨＰ菌感染与活动性胃炎的发生密切相关，而与胃炎的严重程度无显著性差异。并证实了抗ＨＰ菌ＩｇＧ、ＩｇＡ检测具有较高的诊断ＨＰ菌感染的敏感性和特异性。
To understand the immune status of the body during Helicobacter pylori (HP) infection, we measured serum immunoglobulins in 134 patients with upper gastrointestinal disease. The results showed that three serum antibody titers in patients with positive bacterial culture were significantly higher than those in patients with negative bacterial culture. The coincidence rates of serum IgG, IgA, IgM positive and bacterial culture positive were 79.1%, 74.6% and 43.2% respectively. The positive rates of bacterial culture of active gastritis and non-active gastritis were 66% and 42% respectively. Confirmed that HP infection is closely related to the occurrence of active gastritis, but no significant difference with the severity of gastritis. And confirmed the anti-HP bacteria IgG, IgA detection has a higher diagnosis of HP bacterial infection sensitivity and specificity.