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将SARS患者的咽拭子感染Vero E6细胞,用电子显微技术等对SARS病毒进行了研究。结果表明新分离到的病毒粒子没带囊膜时直径大多约50 nm,带有囊膜的直径约100 nm。通过RT-PCR等证明该病毒是新的冠状病毒。这些病毒可与SARS康复患者的血清是强烈的阳性反应,表明此新的冠状病毒是引起SARS主要病原之一。文中还对病毒的发生机制和细胞中的分布进行了探讨。
Viral E6 cells were infected with throat swabs in SARS patients and the SARS virus was studied by electron microscopy. The results showed that the newly isolated virus particles without capsular membrane diameter about 50 nm, with a diameter of about 100 nm capsule. The virus was proved to be a new coronavirus by RT-PCR and the like. These viruses have a strong positive response to sera from SARS-affected patients, indicating that the new coronavirus is one of the major pathogens causing SARS. The article also explores the mechanism of the virus and the distribution of cells.