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目的探讨卵巢颗粒细胞瘤临床分期对其预后和复发的影响。方法回顾性分析吉林大学第二医院1985~2004年收治的保留资料完整的43例卵巢颗粒细胞瘤患者的临床分期因素及预后的关系,并对复发及未复发患者进行上述因素的比较。结果全组总的5年和10年生存率别为95.3%和76.7%。临床分期为Ⅰ期者5年和10年生存率分别为96.4%和92.9%,Ⅱ~Ⅳ期为60.0%和20.0%,分别比较,差异有显著性。不同临床分期的复发情况分别比较,差异有显著性(P<0.05)。复发及未复发,早期复发及晚期复发等各因素相比较,临床分期因素差异有显著性。结论卵巢颗粒细胞瘤的临床分期是其预后的重要相关因素。目前根据临床分期因素尚难以预测患者是否会远期复发。
Objective To investigate the clinical stage of ovarian granulosa cell tumor prognosis and recurrence. Methods The clinical stage and prognosis of 43 patients with preserved ovarian granulosa cell carcinoma who had been preserved in our hospital from 1985 to 2004 were retrospectively analyzed. The above factors were compared between patients with recurrent and non-recurrent cases. Results The overall 5-year and 10-year survival rates were 95.3% and 76.7% respectively. The 5-year and 10-year survival rates were 96.4% and 92.9% in the clinical stage Ⅰ and 60.0% and 20.0% in the stage Ⅱ-Ⅳ, respectively. The difference was statistically significant. The recurrence of different clinical stage were compared, the difference was significant (P <0.05). Recurrence and no recurrence, early recurrence and late recurrence and other factors compared to clinical stage differences were significant. Conclusion The clinical stage of ovarian granulosa cell tumor is an important factor related to its prognosis. According to the clinical stage of the factors is still difficult to predict whether the patient will be long-term recurrence.