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高血糖“代谢记忆”是指糖尿病患者的高血糖状态可对机体不同的组织器官造成持久性损伤,本文从中西医角度出发,论述代谢记忆的西医相关机制:氧化应激、硝化应激、糖基化终产物以及中医“伏邪”“伏毒”理论与“代谢记忆”的联系。在治疗方面,西医提出早期强化血糖控制的原则以及预混胰岛素的优势;而中医则提出活血益气通络的思路在伏邪未发之时进行清透和攻伐。本文中西医并举,罗列对照两者对“代谢记忆”的认识和治则,为后世提供一定的借鉴意义。
Hyperglycemia “Metabolic memory ” refers to the diabetic patients with hyperglycemic state can cause persistent damage to different tissues and organs of the body, this article from the perspective of Chinese and Western medicine, discusses the metabolic memory mechanism of Western medicine: oxidative stress, nitrification stress, Advanced glycation end products and the relationship between Chinese medicine “evil evil ” “poisonous poison ” theory and “metabolic memory ”. In terms of treatment, Western medicine proposed the principle of early intensified glycemic control and the advantages of premixed insulin. However, Chinese medicine proposed the idea of promoting blood circulation and promoting qi through the collaterals. In this article, both medicine and medicine are listed in the article, and the comparison and comparison of both of them are given to the understanding and rules of “metabolic memory” to provide some reference for later generations.