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目前,中西药抗肝纤维化的实验研究已取得可喜进展,四氯化碳(CCl_4)诱导的大鼠肝纤维化模型是经典的研究肝纤维化的模型,本文将近几年中西药抗CCl_4中毒性肝纤维化的实验研究综述如下。 1 中药抗CCl_4实验性大鼠肝纤维化研究 肝纤维化见于胁痛、癥瘕、积聚、臌胀等多种病证,病因病机为湿、热、毒、瘀、痰、郁、虚作用于肝经,使络脉瘀阻,病变常涉及肝脾肾三脏。陆雄等观察旋覆花汤治疗大鼠肝纤维化的作用,结果显示治疗
At present, experimental research on anti-liver fibrosis of Chinese and Western medicine has made gratifying progress. CCl 4 -induced rat liver fibrosis model is a classic model of liver fibrosis. In this paper, Experimental studies on toxic liver fibrosis are summarized below. 1 Chinese medicine anti-CCl 4 experimental rat liver fibrosis Liver fibrosis found in a variety of symptoms such as hypochondriac pain, syndrome, accumulation, bloating, etiology and pathogenesis of wet, heat, poison, stasis, phlegm, depression, In the liver, the collaterals stasis, lesions often involve the liver, spleen and kidney three dirty. Lu Xiong and other observation of Inula Decoction for the treatment of liver fibrosis in rats, the results showed that treatment