本文结合临床病例资料,用RE对110株Ad7进行限制性位点核酸图谱分析。发现近十五年,在长春等地区,Ad7存在7b和7d两个基因组型;优势基因组型由7b转移为7d;7d可能是7b的变异株;7b的毒力、致病性强,7d的毒力相对弱,但致病范围广。7b与7d引起的肺炎等疾病临床特征差异的内在因素、致病基因片段的毒力、致病性等生物学特征不同。 In this paper, clinical case data, with RE RE7 Ad7 restriction site nucleic acid mapping analysis. It was found that in the past fifteen years, there were two genotypes, 7b and 7d, in Ad7. The dominant genotypes were transferred from 7b to 7d, 7b was a 7b mutant, and 7b was virulent. Relatively weak virulence, but a wide range of pathogenic. 7b and 7d pneumonia and other diseases caused by the clinical features of the differences between internal factors, pathogenicity of virulence genes fragment, pathogenicity and other biological characteristics are different.