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设计合成了１２个噻吩骈［３，４－ｄ］嘧啶－２，４－二酮类化合物，其结构经红外光谱、核磁共振光谱、质谱证实。初筛试验表明，大部分化合物具有强心活性，其中化合物ＴＰＤ１２的活性最好
Twelve thieno [3,4-d] pyrimidine-2,4-diones were designed and synthesized. Their structures were confirmed by IR, 1H NMR and MS. Preliminary screening tests showed that most of the compounds have cardiotoxicity and the compound TPD12 is the best