1　资料与方法1 1　对象 :1999年 1月至 2 0 0 0年 6月经胃镜确诊为十二指肠溃疡或胃溃疡病 ,并在 6个月内成功随访的病人 80例 ,均为男性 ,平均每天吸烟 2 6支( 16支～ 60支 )。平均病程 3年 ( 3周～ 32年 )。少数病人为复合性或多发性溃疡。1 2　治疗 :给予雷尼替丁 30 0ｍｇ 1 Materials and Methods 1 1 Subjects: January 1999 to 2000 June by gastroscope diagnosed as duodenal ulcer or gastric ulcer disease, and within 6 months of successful follow-up of 80 patients were male, An average of 26 cigarettes a day (16 to 60). The average duration of 3 years (3 weeks to 32 years). A small number of patients with complex or multiple ulcers. 1 2 treatment: given ranitidine 30 0mg