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本实验应用聚合酶链反应(PCR)技术,对63名不育男子的精液进行了HCMV-DNA检测,发现其中5名男子的精液呈HCMV-DNA阳性,阳性率为7.7％。在这5名男子中,有3名男子的精子WGA/IB检测均呈阳性。另外,我们对63名不育男子的精子计数、活动率、畸型率,精液pH值和白细胞数量等指标进行了观察,发现在HCMV感染者与未感染者之间除了精子计数、白细胞数量略有差别外,其它指标无明显区别。因此我们认为男子生殖道HCMV感染,可能会导致不育,其机理是复杂的,而精子数量减少,精子抗体的产生也许是因素之一。
In this study, HCMV-DNA was detected in semen of 63 infertile men using polymerase chain reaction (PCR) technique. Five of the semen samples were positive for HCMV-DNA, the positive rate was 7.7%. Among the five men, three men had a positive test for WGA / IB sperm. In addition, we observed 63 infertile men’s sperm count, activity rate, malformation rate, sperm pH and white blood cell count and other indicators were observed in HCMV infected and uninfected patients in addition to sperm count, the number of white blood cells slightly Differences, other indicators no significant difference. Therefore, we think that HCMV infection in the male genital tract may lead to infertility. The mechanism is complex, and the number of sperm is reduced, and the production of sperm antibodies may be one of the factors.