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应用改良酶联免疫吸附试验检测122例脑梗塞患者和86例健康对照者血清的IgG和IgM型抗心磷脂抗体(anticardiolipidantibodies,ACA)。结果显示,脑梗塞组ACA阳性率50.8%,对照组ACA阳性率11.6%,两组比较差异非常显著(P<0.01)。初步讨论了ACA的异常增高与脑梗塞之间的关系及可能的致病机理。
Serum IgG and IgM anticardiolipid antibodies (ACA) were detected in 122 patients with cerebral infarction and 86 healthy controls by modified enzyme-linked immunosorbent assay (ELISA). The results showed that the ACA positive rate was 50.8% in cerebral infarction group and 11.6% in control group, the difference was significant (P <0.01). The relationship between ACA abnormality and cerebral infarction and possible pathogenic mechanism were discussed preliminarily.