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目的:观察复方甘草酸苷在尖锐湿疣中的临床疗效,以及对降低尖锐湿疣复发率的作用。方法:120例尖锐湿疣患者按随机化原则分配至治疗组与对照组,治疗组采用高频电针烧灼患处皮疹,术后静脉滴注复方甘草酸苷注射液20~40mL.d-1,10d为1个疗程,可重复2~3疗程,后改用复方甘草酸苷片维持,1片.次-1,3次.d-1,维持至术后第3个月。对照组仅采用高频电针烧灼患处皮疹。结果:治疗组的CD3指标升高高于对照组(治疗组11.36/对照组4.45,P<0.001),复发病例少(治疗组39例/对照组50例,P<0.05),无明显副作用。结论:复方甘草酸苷可升高尖锐湿疣患者细胞免疫CD3值,减少复发。
Objective: To observe the clinical efficacy of compound glycyrrhizin in condyloma acuminatum and to reduce the recurrence rate of condyloma acuminatum. Methods: One hundred and twenty patients with condyloma acuminatum were assigned to the treatment group and the control group according to the principle of randomization. The treatment group was treated with high-frequency electroacupuncture for the rash of the affected area. Intravenous compound glycyrrhizin injection 20 ~ 40mL.d-1,10d For a course of treatment, can be repeated 2 to 3 courses, after the switch to compound glycyrrhizin tablets to maintain, 1. Times -1,3 times .d-1, maintained until the first 3 months after surgery. The control group only used high frequency electroacupuncture burning skin rash. Results: The CD3 index of the treatment group was higher than that of the control group (11.36 in the treatment group and 4.45 in the control group, P <0.001), and there were fewer recurrence cases (39 cases in the treatment group and 50 cases in the control group, P <0.05) with no obvious side effects. Conclusion: Compound glycyrrhizin can increase the cellular immune CD3 value in patients with condyloma acuminatum and reduce recurrence.