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化疗后伴随粒细胞减少及免疫功能低下而合并的感染中,细菌感染占85％。我科于1995年1月～1997年6月早期应用青霉素,积极地预防感染,取得满意疗效。 1 临床资料 肿瘤病人76例,男61例,女15例,年龄26岁～78岁。肺癌22例CAP方案,恶性淋巴瘤10例CHOP方案,胃癌8例FAM方案,乳腺癌8例FAC方案,鼻咽癌19例FBP方案,大肠癌6例FMP方案,精原细胞瘤3例PVB方案,以上每例化疗2个～6个疗程。化疗后每3d～5d复查血常规,监督白细胞下降情况。随机分组各38例,其中治疗组白细胞下降Ⅰ度9例,Ⅱ度18例,Ⅲ度8例,Ⅳ度3例。对照组白细胞下降Ⅰ度9例,Ⅱ度17例,Ⅲ度10
Infections associated with neutropenia and poor immune function following chemotherapy are associated with 85% of bacterial infections. Our department applied penicillin from January 1995 to early June 1997 to actively prevent infection and achieve satisfactory results. 1 Clinical data 76 cases of cancer patients, 61 males and 15 females, aged 26 to 78 years old. 22 cases of lung cancer CAP program, 10 cases of malignant lymphoma CHOP program, 8 cases of gastric cancer FAM program, 8 cases of breast cancer FAC program, 19 cases of nasopharyngeal carcinoma FBP program, 6 cases of colorectal cancer FMP program, seminoma 3 cases of PVB program , Each of the above 2 to 6 cycles of chemotherapy. After 3 days to 5 days after chemotherapy, blood routines were reviewed and leukopenia was monitored. Randomly divided into 38 cases, including the treatment group leukocytes decreased by 1 degree in 9 cases, II degree in 18 cases, III degree in 8 cases, IV degree in 3 cases. In the control group, there were 9 cases of white blood cells falling in degree I, 17 cases in II degree, and 10 degrees in III degree.