论文部分内容阅读
血小板是血液的三大有形成分之一,在止血、伤口愈合、炎症反应、血栓形成、血脂代谢及器官移植排斥等生理和病理过程中具有重要作用[1,2],血小板的研究和临床应用已是现代输血医学和血液学的重要内容之一。血小板的表面有丰富和复杂的抗原,其基因多态性又有种族和群体特征。由于人类血小板抗原(human platelet antigens,HPA)的免疫原性能通过输血、妊娠及药物等免疫因素而产生相应的抗体,
Platelets are one of the three tangible components of blood and play an important role in the physiological and pathological processes such as hemostasis, wound healing, inflammation, thrombosis, lipid metabolism and organ transplant rejection [1,2], platelet research and clinical Application has become an important part of modern blood transfusion medicine and hematology. Platelets have abundant and complex antigens on their surface, and their genetic polymorphism has racial and colony characteristics. Due to the immunogenicity of human platelet antigens (HPA), corresponding antibodies are produced by immune factors such as blood transfusions, pregnancy and drugs,