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目的 进一步探讨毛细支气管炎并心力衰竭的有效治疗方法 ,减少及避免酚妥拉明引起的不良反应。方法 以随机在我院儿科住院的毛细支气管炎并心力衰竭患儿 5 8例作为观察组 ,在常规吸氧、吸痰、镇静、抗感染、纠酸、平喘等治疗的基础上 ,只选用地高辛强心及速尿减轻心脏前负荷 ;另设立对照组 5 0例 ,亦为同期随机住院的毛细支气管炎并心力衰竭患儿 ,在上述治疗的基础上加用酚妥拉明 ,并观察两组患儿的临床治疗效果。结果 观察组与加用酚妥拉明组比较 ,心力衰竭纠正天数无明显差异 (P >0 .0 5 ) ,且避免了因使用酚妥拉明而出现的鼻塞、呼吸困难加重等不良反应。结论 在应用地高辛加强心肌收缩力的基础上 ,加用速尿 ,即可在短期内良好控制毛细支气管炎并发的心力衰竭 ,而无须加用酚妥拉明。
Objective To further explore the effective treatment of bronchiolitis and heart failure, reduce and avoid the adverse reactions caused by phentolamine. Methods Fifty-eight patients with bronchiolitis and heart failure who were hospitalized in pediatric department of our hospital randomly were selected as the observation group. On the basis of routine oxygen inhalation, suctioning, sedation, anti-infective, acid-correcting and antiasthmatic treatment, Digoxin cardiac and furosemide to reduce pre-cardiac load; another set of control group of 50 patients, also for the same period of hospitalized patients with bronchiolitis and heart failure, in addition to the above treatment based on the use of phentolamine and The clinical effects of two groups were observed. Results There was no significant difference between the observation group and the phentolamine group in correcting the number of days of heart failure (P> 0.05), and the avoidance of nasal obstruction due to the use of phentolamine and the worsening of dyspnea were observed. Conclusions In the application of digoxin to enhance myocardial contractility, based on the addition of furosemide, you can in the short term good control of bronchiolitis complicated by heart failure, without the need to add phentolamine.