论文部分内容阅读
目的:探讨胃肠外科围手术期使用抗菌药物情况,指导临床合理用药。方法:总结和分析2013年2月-2014年胃肠外科治疗的220例患者的抗菌药物使用情况。结果:硝基咪唑类200例,使用率90.9%,使用率第1位。第三代头孢菌素类163例,使用率74.1%,使用率第2位。第二代头孢菌素类88例,使用率40.0%,使用率第3位。第一代头孢菌素类36例,使用率16.4%,使用率第4位。氨基糖苷类34例,使用率15.5%,使用率第5位。喹诺酮类27例,使用率12.3%,使用率第6位。第四代头孢菌素类11例,使用率5.0%,使用率第7位。青霉素类8例,使用率3.6%,使用率第8位。Ⅰ类切口单一用药10例(58.8%),二联用药6例(35.3%),三联及以上用药1例(5.9%)。Ⅱ类切口单一用药64例(32.3%),二联用药120例(60.0%),三联及以上用药16例(8.0%)。Ⅲ类切口二联用药1例(33.3%),三联及以上用药2例(66.7%)。结论:胃肠外科手术预防用药基本合理,少数用药指征把握不严,需要及时更改。
Objective: To investigate the use of antimicrobial agents during perioperative period in gastrointestinal surgery and to guide clinical rational drug use. Methods: The antimicrobial use of 220 patients treated by gastrointestinal surgery from February 2013 to 2014 was summarized and analyzed. Results: 200 cases of nitroimidazole, the utilization rate of 90.9%, the use of the first one. The third generation cephalosporins in 163 cases, the utilization rate of 74.1%, the second place. 88 cases of second-generation cephalosporins, the utilization rate of 40.0%, the use of the first three. The first generation of cephalosporins in 36 cases, the utilization rate of 16.4%, the utilization rate of the first four. 34 cases of aminoglycosides, the use rate of 15.5%, the use of the first five. Quinolones in 27 cases, the use rate of 12.3%, the utilization rate of the first six. The fourth generation of cephalosporins in 11 cases, the use rate of 5.0%, the utilization rate of the first seven. Penicillin in 8 cases, the use rate of 3.6%, the use of the first eight. Ⅰ type incision single medication in 10 cases (58.8%), two in six cases (35.3%), triple and above medication in 1 case (5.9%). Sixty-four patients (32.3%) were treated with single incision in type II, 120 patients (60.0%) were treated with two drugs in combination and 16 patients (8.0%) were treated with triple or more drugs. In group Ⅲ, 1 case (33.3%) was used in combination therapy and 2 cases (66.7%) were treated in triple therapy or above. Conclusion: Prevention of gastrointestinal surgery is reasonable and the indications for minority medication are not rigorous and need to be changed in time.