磺酸多相催化剂用于二甲基亚砜中C_6-单糖脱水制5-羟甲基糠醛(英)

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Sulfonic acid-functionalized heterogeneous catalysts have been evaluated in the catalytic dehydration of C(,monosaccharides into 5-hydroxymethylfurfural(HMF) using dimethyl sulfoxide(DMSO)as solvent.Sulfonic commercial resin Amberlyst-70 was the most active catalyst,which was ascribed to its higher concentration of sulfonic acid sites as compared with the other catalysts,and it gave 93 mol%yield of HMF from fructose in 1 h.With glucose as the starting material,which is a much more difficult reaction,the reaction conditions(time,temperature,and catalyst loading) were optimized for Amberlyst-70 by a response surface methodology,which gave a maximum HMF yield of 33 mol%at 147 °C with 23 wt%catalyst loading based on glucose and 24 h reaction time.DMSO promotes the dehydration of glucose into anhydroglucose,which acts as a reservoir of the substrate to facilitate the production of HMF by reducing side reactions.Catalyst reuse without a regeneration treatment showed a gradual but not very significant decay in catalytic activity. Sulfonic acid-functionalized heterogeneous catalysts have been evaluated in the catalytic dehydration of C (, monosaccharides into 5-hydroxymethylfurfural (DMSO) using dimethyl sulfoxide (DMSO) as solvent.Sulfonic commercial resin Amberlyst-70 was the most active catalyst, which was ascribed to its higher concentration of sulfonic acid sites as compared with the other catalysts, and it gave 93 mol% yield of HMF from fructose in 1 h.With glucose as the starting material, which is a much more difficult reaction, the reaction conditions (time, temperature, and catalyst loading) were optimized for Amberlyst-70 by a response surface methodology, which gave a maximum HMF yield of 33 mol% at 147 ° C with 23 wt% catalyst loading based on glucose and 24 h reaction time. DMSO promoted the dehydration of glucose into anhydroglucose, which acts as a reservoir of the substrate to facilitate the production of HMF by reducing side reactions. Catalyst reuse without a regeneration treatment showed a gradual but not very s ignificant decay in catalytic activity.
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