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本文测定167例各种慢性肝病患者血清Ⅲ型前胶原(PCⅢ)、透明质酸(HA)与常规肝功能试验。结果:慢活肝和肝硬化各组血清PCⅢ和HA显著升高,在代偿性肝硬化组中PCⅢ的诊断敏感性显著高于HA,而白蛋白降低、A/G倒置和Y球蛋白升高的敏感性均低于30％。因此诊断肝纤维化和早期肝硬化,仅测常规肝功能试验可造成多数患者漏诊,测定血清PCⅢ和HA有(?)诊断价值。
In this paper, 167 cases of chronic liver disease in patients with serum type Ⅲ procollagen (PC Ⅲ), hyaluronic acid (HA) and conventional liver function tests. Results: The serum PCⅢ and HA in slow-living liver and cirrhosis groups were significantly higher than those in normal liver cirrhosis group. The sensitivity of PCⅢ in decompensated liver cirrhosis group was significantly higher than that in HA group, whereas albumin, A / G inversion and Y- High sensitivity is less than 30%. Therefore, the diagnosis of liver fibrosis and early cirrhosis, only the routine test of liver function tests can cause most patients missed diagnosis of serum PC Ⅲ and HA (?) Diagnostic value.