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乳儿维生素K依赖因子缺乏症是一种家族性。常染色体隐性遗传性疾病。男女两性均可患病。病因主要是维生素K依赖因子缺乏。维生素K依赖因子的合成均需要维生素K。缺乏原因有:(1)婴儿出生后中断了维生素K经过胎盘的供应,而肠道仍呈无菌状态,影响维生素K的合成,致使维生素K无所来源。(2)维生素K依赖因子都是在肝脏内合成,新生儿肝功能不够成熟,影响四种因子的合成。(3)婴儿胆汁中胆酸含量较低而影响维生素K的吸收。(4)胎儿期肝内维生素K贮存不足。另外母体缺乏维生素K时,也将影响婴儿体内维生素K含量。(5)孕妇服用
Infant vitamin K-dependent deficiency is familial. Autosomal recessive genetic disease. Both men and women can be sick. The main cause is the lack of vitamin K-dependent factor. Vitamin K-dependent factor synthesis requires vitamin K. Lack of reasons are: (1) the birth of a baby interrupts the supply of vitamin K through the placenta, while the intestinal tract is still sterile, affecting the synthesis of vitamin K, resulting in no source of vitamin K. (2) vitamin K-dependent factors are synthesized in the liver, neonatal liver function is not mature enough, affecting the synthesis of four factors. (3) infant bile cholic acid content is low and affect the absorption of vitamin K. (4) fetal liver vitamin K storage inadequate. In addition maternal vitamin K deficiency, it will also affect the baby’s vitamin K content. (5) pregnant women taking