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目的对急性前壁心肌梗塞患者加用苯那普利治疗，观察其对梗塞面积及左室收缩功能的近期与远期效果。方法８８例ＡＭＩ患者随机分为苯那普利组（４５例）和常规治疗组（４３例）作为对照。入院即刻、３日、３周、６个月及１年作心电图ＱＲＳ评分，３周、６个月及１年作ＵＣＧ或心血池核素测定以判断左室收缩功能。结果１．苯那普利组ＱＲＳ评分明显降低；２．梗塞面积一直保持在２５．３％左右，未见扩大，而对照组均比苯那普利组扩大；３．ＬＶＥＦ测定在３周、６个月、１年均比对照组明显升高。结论苯那普利对梗塞面积、心电图评分、及心功能方面有明显改善的作用。
Objective To evaluate the short-term and long-term effects of benazepril on acute myocardial infarction patients with infarct size and left ventricular systolic function. Methods 88 patients with AMI were randomly divided into benazepril group (45 cases) and routine treatment group (43 cases) as control. QRS scores of ECG immediately, 3 days, 3 weeks, 6 months and 1 year were collected at admission, and UCG or cardiac pool nuclide was measured at 3 weeks, 6 months and 1 year to determine left ventricular systolic function. Results 1. The benazepril group QRS score was significantly lower; 2. Infarction area has remained at 25.3%, no expansion, while the control group than the benazapril group expanded; 3. LVEF measured at 3 weeks, 6 months, 1 year were significantly higher than the control group. Conclusion Benazepril significantly improved infarct size, ECG score and cardiac function.