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多原发恶性肿瘤(MPMN)首先由Bilroth在1889年描述,当时被视为罕见。作者5年间连续行胃镜检查6481例次,仅发现资料完整的消化道同时性双原发癌3例,现报告如下: 例1,女,70岁。反复出现粘液血便4年,近4个月症状加剧, 日达30余次,伴里急后重感。肛门指诊,直肠后壁触及一个2 x 3 cm菜花状肿物,诊为直肠癌收住院手术,切除标本病理报告为直肠管状腺癌。术后3个月出现吞咽困难,胃镜检查。距门齿25cm处食管壁环状狭窄,病变部位僵硬感,接触出血,拟为食管癌,活检证实为鳞状细胞癌。例2,男,59岁。吞咽困难3个月,伴进食时胸骨后疼痛。胃镜检查;距门齿25cm处食管左侧壁隆起、不平;贲门部前壁僵硬,表面溃疡,活检病理报告:(1)食管鳞状细胞癌。(2)贲门部
Multiple primary malignant tumors (MPMN) were first described by Bilroth in 1889 and were considered rare at the time. The authors performed a total of 6481 consecutive gastroscopy examinations during the past 5 years. Only 3 cases of gastrointestinal complications of double digestive tract were found. The current report is as follows: Example 1, female, 70 years old. Mucus bloody stools recurred for 4 years, and the symptoms intensified in the past 4 months, reaching more than 30 times daily, with a sense of urgency. In the anal examination, a 2 x 3 cm cauliflower mass was touched on the posterior wall of the rectum. The patient was diagnosed as receiving rectal cancer. The pathological report of the specimen was rectal tubular adenocarcinoma. Dysphagia and gastroscopy occurred 3 months after surgery. The esophageal wall was narrow at 25 cm from the incisor, and the stiffness of the lesion site was associated with hemorrhage. It was proposed to be esophageal cancer. Biopsy confirmed squamous cell carcinoma. Example 2, male, 59 years old. Difficulty swallowing for 3 months with back pain in the sternum after eating. Gastroscopy examination; from the incisor 25cm left esophageal wall uplift, uneven; anterior fontanelle stiffness, surface ulcer, biopsy pathology report: (1) esophageal squamous cell carcinoma. (2) Department of Cardia