实验采用冻干处理的异体神经与外源性神经生长因子（ＮＧＦ）结合来桥接大鼠的坐骨神经１．０ｃｍ的缺损。用雄性Ｗｉｓｔａｒ大鼠进行的四组实验结果表明：冻干处理的异体神经可降低其抗原性，但处理后并不损害雪旺氏细胞（ＳＣ）基底膜的完整性，在移植后可能成为轴突再生的通道和支架；外源性ＮＧＦ与冻干神经结合形成的复合体，可为神经的再生提供一个较好的微环境，具有成为理想桥接材料的可能性 Experiments lyophilized allogeneic nerves were used in conjunction with exogenous nerve growth factor (NGF) to bridge a 1.0 cm defect in the rat’s sciatic nerve. Four sets of experiments with male Wistar rats showed that lyophilized allogeneic nerves reduced their antigenicity but did not compromise the integrity of the Schwann cell (SC) basement membrane after treatment and could become axons after transplantation Sudden regeneration channels and scaffolds; the complex formed by the combination of exogenous NGF and lyophilized nerves provides a good microenvironment for nerve regeneration, with the potential to be an ideal bridging material