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目的分析观察磷酸肌酸钠与神经节苷脂早期治疗重度窒息新生儿的疗效。方法选取本院在2012年1月~2012年5月收治的60例存在重度窒息的新生儿作为分析研究对象,然后将他们随机的平均分为治疗组以及对照组,分别选用不同的治疗办法,并对两组新生儿患者的心脏、胃肠道、肾脏器官损伤情况做记录。结果治疗组的临床体征包括意识、多脏器损伤情况、反射、肌张力恢复时间和在第7天、第14天治疗组神经行为评分(NBNA)等明显优于对照组,两组比较差异有统计学意义(P<0.05)。结论磷酸肌酸钠与神经节苷脂早期治疗重度窒息新生儿具有见效快,作用强,并发症少,还能有效地保护重要器官功能,促进临床症状恢复,提高新生儿治愈率。
Objective To analyze the effect of early treatment of neonatal severe asphyxia with sodium creatine phosphate and ganglioside. Methods Sixty newborn infants with severe asphyxia admitted from January 2012 to May 2012 in our hospital were selected as the analysis objects. Then they were randomly divided into treatment group and control group randomly, and then different treatment methods were selected. And the two groups of neonatal cardiac, gastrointestinal, renal organ damage records. Results The clinical signs of the treatment group included consciousness, multiple organ injury, time of reflex and muscle tone recovery, and neurobehavioral score (NBNA) of the treatment group on day 7 and 14, which were significantly better than that of the control group Statistical significance (P <0.05). Conclusion Early treatment of neonatal severe asphyxia with sodium creatine phosphate and ganglioside has the advantages of quick response, strong effect and few complications. It can also effectively protect the vital organs, promote the recovery of clinical symptoms and improve the cure rate of neonates.