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受有丝分裂原或抗原激活的T细胞会在细胞膜上表达白细胞介素Ⅱ受体(IL-2R),并释放可溶性的IL-2R(SIL-2R)到细胞外液中。被激活的巨噬细胞和单核细胞可以产生具有许多生物学活性的肿瘤坏死因子α(TNF-α)。作者测定了54例肾移植病人和51名健康人的血浆SIL-2R和TNF-α水平,并对其临床意义进行了分析。
Mitogen-activated or antigen-activated T cells express interleukin-2 receptor (IL-2R) on the cell membrane and release soluble IL-2R (SIL-2R) into the extracellular fluid. Activated macrophages and monocytes can produce tumor necrosis factor alpha (TNF-alpha) with many biological activities. The authors measured plasma levels of SIL-2R and TNF-α in 54 renal transplant recipients and 51 healthy individuals and analyzed their clinical implications.