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[目的]探讨益肾化痰逐瘀中药治疗多发性骨髓瘤的疗效。[方法]收集血液科门诊符合纳入标准的多发性骨髓瘤患者40例,给予益肾化痰逐瘀中药治疗,对比用药前后的中医临床疗效及实验室检测指标的变化。[结果]中医疗效评价临床痊愈14例(35%),显效14例(35%),有效10例(25%),无效2例(5%),有效率为95%。全组未见明显不良反应。治疗前后血β2微球蛋白、骨髓浆细胞比例、血红蛋白、KPS体能评分均有明显改善(P<0.05)。[结论]益肾化痰逐瘀中药治疗多发性骨髓瘤疗效显著,值得临床推广。
[Objective] To investigate the curative effect of Yishen Huatan Zhuyu Traditional Chinese Medicine on multiple myeloma. [Methods] Forty patients with multiple myeloma who met the inclusion criteria were collected in Department of Hematology. The patients were given Yishen Huatanzhuyu Chinese herbal medicine before and after treatment, and the changes of clinical curative effect and laboratory test indexes were compared. [Result] 14 cases (35%) were cured in clinical curative effect evaluation, 14 (35%) were effective, 10 (25%) were effective, 2 (5%) were ineffective and the effective rate was 95%. The whole group showed no obvious adverse reactions. Blood β2 microglobulin, bone marrow plasma cell ratio, hemoglobin, KPS physical fitness scores were significantly improved before and after treatment (P <0.05). [Conclusion] Yishen Huatanzhuyu traditional Chinese medicine treatment of multiple myeloma significant effect, worthy of clinical promotion.