5-fluorouracil相关论文
替加氟是一种转化为5-氟尿嘧啶的口服化疗前药,主要通过抑制胸苷酸合酶激活并杀死肿瘤细胞.本研究通过取代、水解、缩合合成了20种......
Chemotherapy-related fatigue (CRF) is increasingly being recognized as one of the severe symptoms in patients undergoing......
The potential application of a designed self-assembly peptide CH3CO-Pro-Thr-Phe-Cys-Phe-Lys-Phe-Glu-Pro-NH2 (named as P1......
Curcumin Reverses 5-Fluorouracil Resistance by Promoting Human Colon Cancer HCT-8/5-FU Cell Apoptosi
Objective:To investigate the potential mechanisms that curcumin reverses 5-fluorouracil (5-FU) multidrug resistance (MDR......
Galactosylated chitosan/5-fluorouracil nanoparticles inhibit mouse hepatic cancer growth and its sid
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Orotate phosphoribosyl transferase mRNA expression and the response of cholangiocarcinoma to 5-fluor
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Glyoxalated chitosan-5-fluorouracil/chitosan-folate as colon-specific and colon cancer cell-targeted
Colon cancer refers to cancerous growth in colon,rectum or cecum [1].Oral anti-cancer drug has been advocated as adjuvan......
Polymer vesicles assembled from ALG-g-PNIPAM and β-cyclodextrin through inclusion complexation for d
Polymer vesicles prepared from self-assembly of amphiphilie block or graft copolymers have been extensively studied for ......
5-Fluroruracil (5FU) is used as a chemotherapeutic agent in modem medicine.However,due to its low solubility at physiolo......
Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for trea
Objective: This study compared the effectiveness of triamcinolone acetonide alone and in combination with 5-fluorouracil......
5-Fluorouracil combined with cisplatin via arterial induction for advanced T-stage nasopharyngeal ca
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5-FU-induced up-regulation of exosomal PD-L1 reflects immunosuppression in gastric cancer patients a
Objective Although 5-Fluorouracil(5-FU),an important clinical cytotoxic chemotherapy drug,has been thought to directly k......
Hyperglycemia associated with 5-fluorouracil-based chemotherapy negatively impacts outcome of colore
Objective: To explore the association between 5-FU-basedchemotherapy associated hyperglycemia and 5-year outcome of CRC ......
5-Fluorouracil(5-FU)is a well-known antitumour agent widely used for the treatment of solid tumors.However,its clinical ......
Co-encapsulation of doxorubicin and 5-fluorouracil based on amphiphilic dendritic nanomicelle for sy
Combination cancer therapy has attracted considerable attention due to its advantages of enhancing antitumor efficacy by......
Aim: Reg4 is a member of the Reg multigene family,and is highly up-regulated in many gastrointestinal cancers.Gastric ca......
Objective Chemoresistance is one of the key factors that affecting the outcome of patients with gastric cancer,and it is......
Background&Aims BCL6B is a potential tumor suppressor in human gastric cancer, but the regulation and mechanism of BCL6B......
Objective To explore the relationship between single nucleotide polymorphisms (SNP) of dihydropyrimidine dehydrogenase (......
Background The aim was to develop a slow-release poly-lactic-co-glycolic acid (PLGA)-5-fluorouracil microsphere, study t......
Continuous 5-fluorouracil infusion in inoperable malignant bowel obstruction Running head: 5-fluorou
Context: Malignant bowel obstruction is a common complication in advanced cancer patients with abdominal or pelvic malig......
Study on tumor-targeted delivery of anticancer agent using polyethylene glycol derivatives as drug c
Cancer is one of the main causes leading to death,which seriously endangers human health and survival.Traditional chemot......
The NLRP3 inflammasome activated by reactive oxygen species in 5-fluorouracil-chemoresistance of ora
Objective:5-fluorouracil (5-FU) is a standard chemotherapeutic agent for local and distant metastatic oral squamous cell......
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Concurrent chemoradiotherapy comparison of taxanes and platinum versus 5-fluorouracil and platinum i
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本文以典型抗癌药5-氟尿嘧啶（5-Fu）为对象，研究了Fenton法和草酸钠-Fenton法对5-FU的降解效果与反应动力学．结果表明，在pH值为3，Fe^2＋浓度......
以3-硝基-4-甲基苯甲酸为原料,经酯化、溴化,再与2,4-双-三甲基硅烷氧基-5-氟尿嘧啶反应,最后水解合成了标题化合物,有关中间体及......
目的：通过动物试验观察苏拉明复合粘弹剂与5-氟尿嘧啶(5-Fu)眼内灌注对大鼠后发性白内障的影响。方法30只健康大鼠制作白内障大鼠模......
目的：观察环磷酰胺联合吡柔比星﹑5-氟尿嘧啶的新辅助化疗方案即(CTF方案)诊疗Ⅲ期乳腺癌的疗效。方法经穿刺﹑彩超﹑钼靶摄片证实为Ⅲ期......
目的 探讨DCF方案(多西紫杉醇+顺铂+5-氟尿嘧啶)与ECF方案(表柔比星+顺铂+ 5-氟尿嘧啶)治疗进展期胃癌的临床疗效及不良反应.方法 ......
目的:制备携带氟尿嘧啶(5-FU)复乳的温度敏感凝胶,采用Caco-2细胞模型考察其转运吸收特性。方法:采用两步复乳法制备5-FU复乳,以泊......
目的：观察并分析奈达铂（NDP）与5-氟尿嘧啶（5-FU）联合治疗方案对于食管癌治疗的疗效和安全性。方法：选取50例食管癌患者随机分成NF（NDP/5-F......
目的 观察5-氟尿嘧啶(5-FU)对重症感染大鼠致炎细胞因子和抗炎细胞因子的调节作用,探讨5-FU对重症感染大鼠保护作用的机制.方法 将......
目的 探讨转录因子激活蛋白2E(transcription factor activator protein 2E,TFAP2E)在胃癌细胞株的甲基化水平及其对5-氟尿嘧啶(5-......
AIM: To evaluate the efficacy of combination chemotherapy with interferon-α(IFNα) and 5-fluorouracil(5-FU) in patients......
Successful treatment of advanced hepatocellular carcinoma by combined administration of 5-fiuorourac
We report a case of hepatocellular carcinoma (HCC) treated successfully by transarterial chemoembolization (TACE) follow......
Anti-hepatocarcinoma effects of 5-fluorouracil encapsulated by galactosylceramide liposormes in vivo
AIM: To study the anti-hepatocarcinoma effects of 5fluorouracil (5-Fu) encapsulated by galactosylceramide liposomes (5-F......
CpG oligodeoxynucleotides inhibit tumor growth and reverse the immunosuppression caused by the thera
AIM: To investigate the effect of CpG-containing oligodeoxynucleotides (CpG ODN) alone or in combination with the chemot......
Activity and safety of pegylated liposomal doxorubicin,5-fluorouracil and folinic acid in inoperable
AIM: To improve the results of New therapeutic strategies in hepatocellular carcinoma (HCC). We have conducted a phase ......
Effects of endogenous nitric oxide induced by 5-fluorouracil and L-Arg on liver carcinoma in nude mi
AIM: To study the effects of endogeous nitric oxide induced by 5-fluorouracil (5-FU) and L-arginine (L-Arg)on the human ......
Thymidylate synthase and thymidine phosphorylase gene expression as predictive parameters for the ef
AIM: To investigate the prognostic role of thymidylate synthase (TS) and thymidine phosphorylase (TP)mRNA levels in T3 o......
Twenty-four hour intra-arterial infusion of 5-fluorouracil,cisplatin, and leucovorin is more effecti
AIM: To evaluate the time dependence of intra-arterial 5-fluorouracil (5-FU) therapy for advanced hepatocellular carcino......
Objective: To investigate the effects of quercetin(Q) and rutin on 5-fluorouracil(5-FU)-induced hepatotoxicity.Methods: ......
Preparation of chitosan-polyaspartic acid-5-fluorouracil nanoparticles and its anti-carcinoma effect
AIM: To prepare chitosan-polyaspartic acid-5-fluorouracil (CTS-Pasp-5Fu) nanoparticles and investigate its anti-carcinom......
