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Inactivation of SAM-methyltransferase is the mechanism of attenuation of an historic louse borne typ
Louse borne typhus(also called epidemic typhus)was one of mans major scourges and epidemics of the disease can be reigni......
AIM:Polo-like kinase 1 (PLK1) serine/threonine kinaseplays a vital role in multiple phases of mitosis in gastriccancer ......
对携带兔斯氏艾美耳球虫微线蛋白-5基因（MIC-5）真核表达质粒asd-pBMIC-5-IL-15的减毒鼠伤寒沙门菌X4550（X4550/asd-pBMIC-5-IL-15）进行......
Silks represent some of the most precious ancient and historic textile artefacts in collections worldwide.Their optimum ......
AIM: To study the 5-HT responses in stomach fundus from Steptozotocin (STZ)-induced diabetic rats in comparison with ca......
Ginsenoside Rb1 Attenuates Isoflurane/surgery-induced Cognitive Dysfunction via Inhibiting Neuroinfl
Objective Anesthetic isoflurane plus surgery has been reported to induce cognitive impairment. The underlying mechanism ......
Limited brain magnetic resonance imaging(MRI) consisting of axial fluid attenuated inversion recovery, axial diffusion w......
AIM:To study the effect of cholecystokinin-octapeptide(CCK-8)on lipopolysaccharide(LPS)-induced pulmonaryartery smooth ......
Background Stimulation of the heart β_3-adrenoceptor(AR)may result in a negative inotropic effect.Being up-regulated,......
Induction of deletion mutation on ompR gene of Salmonella enterica serovar Typhi isolates from asymp
Objective:To develop allenualed slrains of Salmonella enterica serorar Typhi(S.typhi) for the candidate vaccine by osmol......
Effect of amino acid mutation at position 127 in 3A of a rabbitattenuated foot-and-mouth disease vir
An amino acid mutation(R127→I) in the 3A non-structural protein of an FMDV serotype Asia1 rabbit-attenuated ZB strain w......
Objective To investigation on novel pharmacological target against pulmonary hypertension.It was recognized in the recen......
Epigallocatechin-3-gallate attenuates lipopolysaccharideinduced inflammation in human retinal endoth
AIM:To investigate the mechanism underlying the anti-inflammatory effects of epigallocatechin-3-gallate(EGCG)in lipopoly......
Morphine prevents mitochondrial oxidative stress at reperfusion by activating mitochondrial Src tyro
AIM:To address the role of the mitochondrial Src tyrosine kinase and mitochondrial oxidative stress in the cardioprotect......
Effect of hepatocyte growth factor and transforming growth factor-β_1 on atrial fibroblasts fibrosis
Objective To investigate the effect of hepatocyte growth factor (HGF) and transforming growth factor-β1 (TGFβ1) on the......
Numerical Simulation on Broad-band Er-doped Superfluorescent Fiber Source Filter Using Long Period C
Given is an analysis of broad-band Er-doped superfluorescent fiber source(EDSFS)filter using long period chirped fiber g......
CYP2J2-derived EETs attenuated Angiotensin Ⅱ-induced adventitial remodeling via reduced inflammatory
BACKGROUND: Cytochrome P450( CYP) epoxygenases metabolize arachidonic acids( AA) to form epoxyeicosatrienoic acids (EETs......
Further Report on Carcinogenesis or Tumorigenicity ofMDCK Canine Kidney Cell(CKC) Lines and Analysis
Using Hela cell cultures as positive control and primary canine kidney cell (CKC) or feline kidney cell (FKC) cultures ......
AIM:To investigate the effect of cell adhesion molecule P-selectin monoclonal antibody (Mab) on metastasis andimmune fu......
Development of an oral DNA vaccine against MG7-Ag of gastric cancer using attenuated salmonella typh
AIM:To develop an oral DNA vaccine against gastric cancerand evaluate its efficacy in mice.METHODS:The genes of the MG7......
Realistic representation of the earth may be achieved by combining the mechanical properties of elastic solids and visc......
Diallyl disulfide-induced G2/M arrest of human gastric cancer MGC803 cells involves activation of p3
AIM:To determine the role of p38 MAP kinase signaltransduction pathways in diallyl disulfide (DADS)-inducedG2/M arrest ......
AIM: To develop an oral attenuated Salmonella typhimurium vaccine against gastric cancer and to evaluate its efficacy in......
Frequency and Voltage-dependent Inhibition of Delayed Outward Potassium Current by Flecainide in Iso
Effects of flecanide on membrane currents were studied using an isolated single atrial cell from guinea pig hearts. The......
Prophylaxis of tumor through oral administration of IL-12 GM-CSF gene carried by live attenuated sal
A live attenuated AraA autotrophic mutant of Salmonella typhimurium (SL3261) was used as carrier for eukaryotic expressi......
From the microstructure of heat radiation, the interaction between the incident heat radiative wave and the electromag-......
A simple, sensitive and non-destructive technique for characterizing bovine dental enamel erosion:at
Although many techniques are available to assess enamel erosion in vitro, a simple, non-destructive method with suf fi c......
By citrate sol-gel auto-combustion method,the nanophase M-type planar hexagonal ferrite is prepared.The transmission ele......
Effect of Radix Paeoniae Rubra on the expression of HO-1 and iNOS in rats with endotoxin-induced acu
Objective: To investigate the effect of Radix Paeoniae Rubra (RPR) on the expression of heme oxygenase (HO-1) and induce......
Decreased expression of human aquaporin-5 correlated with mucus overproduction in airways of chronic
Aim:To investigate the relationship between aquaporin-5(AQP_5)expression andmucus overproduction in the airways of Chin......
Blockade of the receptor for advanced glycation end product improves immune response and survival in
AIM:The receptor of advanced glycation endproducts(RAGE)is a pattern-recognition receptor that binds diverse classes of ......
Aim:Liver fibrosis represents a process of healing and scarring in response tochronic liver injury.Effective therapies ......
Thermodynamic processes of ice in three lakes and landfast ice around Zhongshan Station, Antarctica, were observed in 20......
Mechanisms for regulation of gastrin and somatostatin release from isolated rat stomach during gastr
AIM:To investigate the intragastric mechanisms forregulation of gastric neuroendocrine functions during gastricdistenti......
AIM: To analyze the hepatic and intestinal microcirculation in an animal model of liver cirrhosis and inflammatory bowel......
BACKGROUND:At present, the most common examination modality for diffuse axonal injury (DAI) is CT or MRI. However, both ......
Eubacterium limosum ameliorates experimental colitis and metabolite of microbe attenuates colonic in
AIM:To examine the effect of Eubacterium limosum(E.limosum)on colonic epithelial cell line in vitro,and toevaluate the ......
AIM: To evaluate the effects of betaine on the ethanol-induced secretion of IGF-I and IGFBP-1 using radioim-munoassay an......
Electroacupuncture-attenuated ischemic brain injury increases insulin-like growth factor-1 expressio
Acupuncture has recently gained popularity in many countries as an alternative and complementary therapeutic interventio......
Effect of morphine preconditioning on neuronal apoptosis following cerebral ischemia/reperfusion inj
Apoptosis,a form of neuronal damage,takes place following cerebral ischemia/reperfusion injury,and caspase-3 plays an im......
Age-related changes in cerebral angiogenesis and fetal liver kinase-1 expression after cerebral isch
Cerebral angiogenesis in the early stages after cerebral ischemia injury is essential for the recovery of nerve function......
Inhibition of hepatic interleukin-18 production by rosiglitazone in a rat model of nonalcoholic fatt
AIM:To investigate the effects of rosiglitazone(RGZ) on expression of interleukin-18(IL-18) and caspase-1 in liver of no......
It is difficult to control the degree of ischemic postconditioning in the brain and other isch-emia-sensitive organs. Re......
A recombinant plasmid pMM-CTB containing the gene for production of the nontoxic B subunit of Vibrio cholera was transfe......
AIM:To determine the molecular mechanisms of Shugan decoction(SGD) in the regulation of colonic motility and visceral hy......
In this paper,polyimide(PI)films are modified using an atmospheric pressure plasma generated by a dielectric barrier dis......
AIM: To investigate the role of key iron-regulatory protein, hepcidin in non-alcoholic fatty liver disease(NAFLD). METHO......
Neuroprotective effects of ischemic preconditioning on hippocampal CA1 pyramidal neurons through mai
Ischemic preconditioning elicited by a non-fatal brief occlusion of blood flow has been applied for an experimental ther......
